Question 01) Explanation :
Penicillin inhibits cell wall synthesis in susceptible bacteria, inhibits transpeptidase 》 prevents peptidoglycan synthesis 》 cell wall deficient forms 》 autolysis 》 cell death 》 Bactericidal effect.
Neostigmine is a quaternary ammonium compound, directly stimulates the Nm receptors at NMJ. Thus it improves muscle power in patients with Myasthenia gravis.
Pyridostigmine features are same as Neostigmine. Pyridostigmine is preferred over Neostigmine in Myasthenia gravis because it has longer duration of action.
Question 03) Explanation :
Reserpine is chief chemical constituent of Rauwolfia, and its structure contains beta carboline ring, and it is also used as adrenergic blocker.
Question 06) Explanation :
Pyrazinamide is converted to pyrazinoic acid by mycobacterial pyrazinamidase and distrupts cell membrane metabolism and transport function.Chloramphenicol binds with 50s ribosome and prevents peptide bond formation between the newly attached amino acid and peptide chain.
Omeprazole : supresses gastric acid secretion : Gastro esophageal reflux, Peptic ulcer.
Question 08 Explanation :Atropine is an antimuscarinic
Dexamethasone is used to treat allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.Deferoxamine is used in iron poisioning.
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